TRANSVAC: Collaborative network’s role in boosting Vax2Muc’s vaccine research

In the world of vaccine research, innovations are constantly emerging to address the evolving challenges posed by bacterial infections. Vax2Muc is one such initiative, focusing on developing vaccines that induce a strong mucosal immune response and long-term protection from pathogens residing in the stomach, such as H.Pylori. This is the project’s main target and a leading cause of gastric cancer. The current treatment of H.Pylori infection includes antibiotics, but treatment success is hampered by rising antimicrobial resistance. Research into alternative approaches to tackling these kinds of bacterial infections is therefore urgent and highly impactful.

To reach the project’s goals and move the cancer vaccine science forward, collaboration is key. TRANSVAC was a collaborative network designed to provide comprehensive support to vaccine developers and offer access to crucial vaccine development infrastructure. From early-stage research to clinical trials, TRANSVAC has helped advance vaccine technology and has become a vital resource for researchers working on both traditional and novel vaccine approaches. A recent article "Boosting Vaccine Research: The 16-Year Journey of TRANSVAC Vaccine Infrastructure," sheds light on the crucial role that the TRANSVAC infrastructure has played in supporting vaccine research including the EU funded project Vax2Muc.

Vax2Muc’s work benefits significantly from the robust network of services and tools offered by TRANSVAC. One example is the availability of key vaccine candidate ingredients through the network.

The two initiatives are prime examples of how EU-funded projects are pushing the boundaries of medical research. Vax2Muc is opening the door to new ways of tackling diseases, particularly those that affect mucosal surfaces, as well as addressing the ever-growing problem of antimicrobial resistance.

By accelerating the development of novel vaccine technologies, these projects, through collaboration, are contributing to the creation of more effective and accessible vaccines, paving the way for a healthier future.

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“Vaccine development addresses the root cause of AMR”: Interview with Vax2Muc coordinator Prof Dr Markus Gerhard